34 Addiction Treatment Centers in Greenville, SC

Browse verified addiction treatment centers in Greenville, South Carolina. Compare providers and find contact information.

Recovery Centers of America at Greenville

★★★★½ (221 reviews)
47 Fisherman Ln, Greenville, SC 29615
(855) 390-6568
Website: recoverycentersofamerica.com/locations/greenville
Hours: Mon-Sun: Open 24 hours

Encompass Health Rehabilitation Hospital of Greenville

★★★★½ (151 reviews)
3372 Laurens Rd, Greenville, SC 29607
(864) 537-4600
Website: www.encompasshealth.com/locations/greenville-rehab
Hours: Mon-Sun: Open 24 hours

Solutions Recovery Center, Inc

★★★★☆ (166 reviews)
520 Lowndes Hill Rd, Greenville, SC 29607
(864) 567-7010
Website: www.solutionsrecoverycenter.com
Hours: Mon: 8 AM–6 PM | Tue: 8 AM–6 PM | Wed: 8 AM–6 PM | Thu: 8 AM–6 PM | Fri: 8 AM–6 PM | Sat: Closed | Sun: Closed

The Turning Point of South Carolina

★★★★☆ (122 reviews)
24 Bruce Rd, Greenville, SC 29605
(864) 299-0090
Website: www.turningpointofsc.org
Hours: Mon-Sun: Open 24 hours

Phoenix Center

★★★☆☆ (101 reviews)
1400 Cleveland St, Greenville, SC 29607
(864) 467-3790
Website: www.phoenixcenter.org
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–3 PM | Sat: Closed | Sun: Closed

Southside Medical and Laser Center

★★★★★ (51 reviews)
3919 SC-14, Greenville, SC 29615
(864) 288-2006
Website: www.southsidemc.com
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–12 PM | Sat: Closed | Sun: Closed

Crossroads Treatment Center of Greenville, SC

★★★★☆ (51 reviews)
157 Brozzini Ct Suite A, Greenville, SC 29615
(877) 848-9810
Website: www.crossroadstreatmentcenters.com/center/crossroads-of-greenville-sc
Hours: Mon: 5–11 AM | Tue: 5–11 AM | Wed: 5–11 AM | Thu: 5–11 AM | Fri: 5–11 AM | Sat: Closed | Sun: Closed

FAVOR Upstate - Greenville Center

★★★★★ (35 reviews)
355 Woodruff Rd #303, Greenville, SC 29607
(864) 385-7757
Website: favorupstate.org
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Lighthouse Care and Counseling | Suboxone Clinic

★★★★½ (37 reviews)
6257 White Horse Rd, Greenville, SC 29611
(864) 283-0745
Hours: Mon: 6 AM–2 PM | Tue: 6 AM–2 PM | Wed: Closed | Thu: 6 AM–2 PM | Fri: 6 AM–2 PM | Sat: Closed | Sun: Closed

Greenville Metro Treatment Center

★★★☆☆ (46 reviews)
602 Airport Rd C, Greenville, SC 29607
(864) 234-7952
Website: www.newseason.com/clinics/greenville-metro-treatment-center
Hours: Mon: 5 AM–1:30 PM | Tue: 5 AM–1:30 PM | Wed: 5 AM–1:30 PM | Thu: 5 AM–1:30 PM | Fri: 5 AM–1:30 PM | Sat: Closed | Sun: Closed

Miracle Hill Overcomers Center

★★★★★ (24 reviews)
1916 N Pleasantburg Dr #4036, Greenville, SC 29609
(864) 631-0088
Website: miraclehill.org/how-we-help/addiction-recovery/overcomers-program
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Vertical Treatment Centers

★★★★☆ (27 reviews)
142 Milestone Way, Greenville, SC 29615
(864) 991-8884
Website: www.verticaltreatmentcenters.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–1 PM | Sat: Closed | Sun: Closed

Alano Club of the Piedmont

★★★★★ (21 reviews)
111 Catalina Dr, Greenville, SC 29609
(864) 268-2240
Hours: Mon: 8 AM–7 PM | Tue: 8 AM–7 PM | Wed: 8 AM–7 PM | Thu: 8 AM–7 PM | Fri: 8 AM–7 PM | Sat: Closed | Sun: Closed

Cypress Center

★★★★½ (22 reviews)
103 S Venture Dr, Greenville, SC 29615
(864) 419-4424
Website: www.cypresscenter.net
Hours: Mon: 9 AM–3 PM | Tue: 9 AM–3 PM | Wed: 9 AM–3 PM | Thu: 9 AM–3 PM | Fri: 12–2 PM | Sat: 9:30 AM–12 PM | Sun: Closed

Greenville Transitions Recovery Center, LLC

★★★★½ (17 reviews)
25 Sweetbriar Rd Suite A-4, Greenville, SC 29615
(864) 528-3370
Website: www.greenvilletransitionsrecoverycenter.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Sellman Gary K MD

★★★★☆ (18 reviews)
6257 White Horse Rd, Greenville, SC 29617
(864) 283-0745
Website: www.facebook.com/Lighthousecareandcounseling
Hours: Mon: 6 AM–2 PM | Tue: 6 AM–2 PM | Wed: Closed | Thu: 6 AM–2 PM | Fri: 6 AM–2 PM | Sat: Closed | Sun: Closed

Miracle Hill Renewal Center

★★★★☆ (16 reviews)
19 Graves Dr, Greenville, SC 29609
(864) 242-2166
Website: miraclehill.org/how-we-help/addiction-recovery/miracle-hill-renewal-program
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Prisma Health Roger C. Peace Outpatient Rehabilitation–Augusta St.

★★★½☆ (18 reviews)
100 Augusta St, Greenville, SC 29601
(864) 455-2626
Website: prismahealth.org/locations/ambulatory-labs-other/rcp-rehabilitation-augusta
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Julia Rodriguez, Psychiatric Nurse Practitioner

★★★★★ (11 reviews)
30 Patewood Dr Building 2, Suite 160, Greenville, SC 29615
(864) 823-6649
Website: lifestance.com/provider/nurse-practitioner/sc/greenville/julia-rodriguez
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Solid Foundation Counseling Services, LLC

★★★★½ (12 reviews)
207 W Antrim Dr, Greenville, SC 29607
(864) 614-1407
Website: solidfoundationcounseling.com

Life Line Services - Substance Abuse Treatment

★★★★½ (10 reviews)
16 Mills Ave #8, Greenville, SC 29605
(864) 775-5509
Website: lifelinesvcs.com
Hours: Mon: Closed | Tue: 6 AM–2 PM | Wed: 6 AM–2 PM | Thu: 6 AM–2 PM | Fri: 8 AM–2 PM | Sat: Closed | Sun: Closed

Serenity Village

★★★★☆ (9 reviews)
6 Dunean St, Greenville, SC 29611
(864) 467-3881
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Greenville Suboxone Clinic

★★★½☆ (5 reviews)
81 Pointe Cir Suite A, Greenville, SC 29615
(864) 499-8360
Website: www.greenvillesuboxoneclinic.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–1 PM | Sat: Closed | Sun: Closed

Greenville Recovery Center

★★★★★ (3 reviews)
24 Park Woodruff Dr Suite 100A, Greenville, SC 29607
(864) 215-4500
Website: recoverycentercarolinas.com/greenville
Hours: Mon-Sun: Open 24 hours

Alain Harris Litwin, MD

★★★★★ (3 reviews)
876 W Faris Rd, Greenville, SC 29605
(864) 455-5648
Website: doctors.prismahealth.org/provider/Alain+Harris+Litwin/995988

Safe Haven Recovery

★★★★★ (2 reviews)
211 Century Dr, Greenville, SC 29607

Thais Harris, Counselor

★★★★★ (2 reviews)
30 Patewood Dr Building 2, Suite 160, Greenville, SC 29615
(864) 823-6649
Website: lifestance.com/provider/therapist/sc/greenville/thais-harris
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Imperial Rehab Center Greenville, SC

★★★★★ (1 reviews)
6619 White Horse Rd, Greenville, SC 29611
(864) 519-8328
Hours: Mon-Sun: Open 24 hours

Upstate Intergroup Office

★★★★★ (1 reviews)
1302 Rutherford Rd Side Entrance (Orange Awning, Greenville, SC 29609
(864) 233-6446
Website: www.upstateintergroup.org
Hours: Mon: 10 AM–2 PM | Tue: 10 AM–2 PM | Wed: 10 AM–3 PM | Thu: 10 AM–3 PM | Fri: 10 AM–2 PM | Sat: Closed | Sun: Closed

Prisma Health Recovery Clinic–Greenville

876 W Faris Rd, Greenville, SC 29605
(864) 455-5994
Website: prismahealth.org/locations/practices/recovery-clinic-greenville
Hours: Mon: 8 AM–4 PM | Tue: 8 AM–4 PM | Wed: 8 AM–4 PM | Thu: 8 AM–4 PM | Fri: 8 AM–12 PM | Sat: 8 AM–4 PM | Sun: 8 AM–4 PM

Greenville County Commission

1400 Cleveland St, Greenville, SC 29607
(864) 467-3076
Website: www.greenvillecounty.org/Council/boardscomm.aspx
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

A Alcohol Abuse Access

Greenville, SC 29601
(864) 235-3735

Hope for Families

136 Milestone Way, Greenville, SC 29615
(864) 906-2395
Website: www.familyrecoveryacademy.online

Adetunji Adenipekun, Psychiatric Nurse Practitioner

30 Patewood Dr Building 2, Suite 160, Greenville, SC 29615
(843) 501-1099
Website: lifestance.com/provider/nurse-practitioner/sc/greenville/adetunji-adenipekun
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

About Addiction Treatment Centers in Greenville, SC

Finding the right support in Greenville, South Carolina, begins with understanding that addiction touches every part of our community—from the bustling downtown workforce to the quiet neighborhoods along the Reedy River. Whether you’re facing substance use yourself or supporting a loved one, the path to recovery is deeply personal and available. Greenville’s rapid growth has brought both opportunity and stress, making access to compassionate, professional care more important than ever.

Addiction does not discriminate; it affects people of all ages, backgrounds, and professions across the Upstate. A treatment center in Greenville can provide a structured, judgment-free environment where you can step away from daily pressures and focus on healing. These local programs are designed to meet you where you are, offering medical support, therapy, and community connections that honor your strength and resilience.

You deserve care that respects your dignity and your unique story. BeforeRehab.com helps you explore Greenville’s treatment options with clarity, so you can move forward with hope and the right support by your side.

Frequently Asked Questions

How many addiction treatment centers are in Greenville?

Our directory lists 34 addiction treatment facilities in Greenville, SC.

What types of addiction do treatment centers handle?

Most addiction treatment centers treat a range of substance use disorders including alcohol, opioids, stimulants, benzodiazepines, and other drugs. Some also treat behavioral addictions. Contact facilities directly to confirm they treat your specific concern.

How long does addiction treatment take?

Treatment length varies by individual need. Programs range from 30 days to 90 days or longer for residential treatment. Outpatient programs may continue for several months. Research suggests longer treatment durations are associated with better outcomes.

BeforeRehab.com is an informational directory only. We are not a treatment provider, referral service, or crisis hotline. The information provided does not constitute medical advice. Always verify a facility's credentials, licensing, and insurance acceptance directly. If you or someone you know is in crisis, please call 988 (Suicide & Crisis Lifeline) or SAMHSA's National Helpline at 1-800-662-4357.

Listings are displayed in no particular order. No facility has paid for placement in this directory.

This is not a referral service. We do not endorse or recommend any facility listed.

Business owners: to update or remove a listing, email info@beforerehab.com.

Verify credentials with your State Licensing Authority.

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Important: This website does not provide referrals to any treatment facility. BeforeRehab.com does not receive compensation, kickbacks, or fees of any kind from any treatment center, sober living home, or recovery service listed on this site. No facility has paid for placement, priority positioning, or endorsement. All listings are derived from publicly available data and appear in no particular order. If you need immediate help, call the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).